Zuckerberg and Chan aim to tackle all disease by 2100

Priscilla Chan was trained as a paediatrician

Facebook's founder Mark Zuckerberg and his wife Priscilla Chan have pledged $3bn (£2.3bn) to fund medical research over the next decade.

At a press conference in San Francisco, they said their ultimate goal was to "cure, prevent or manage all diseases by the end of the century". The funds will be distributed by the Chan Zuckerberg Initiative, which they created in December 2015.

Mr Zuckerberg believes today's newborns will typically live beyond 100

Tech leaders are increasingly turning their attention to health. Earlier in the week, Microsoft said it intended to "solve" cancer by using artificial intelligence tools.

Bill Gates said his hosts were making an "incredible commitment to research and development"

Google's DeepMind unit is working with the NHS to find a way to use computers to more accurately diagnose diseases. And IBM and MIT announced a tie-up earlier this week to develop AI-based systems that could help clinicians improve the care of elderly and disabled patients.

Mr Zuckerberg and Ms Chan set up their philanthropic company following the birth of their daughter Max

Even so, the Chan Zuckerberg plan is marked by its ambition.

Biohub projects

Mr Zuckerberg said that at present 50 times more money was spent on treating people who are sick than on curing the diseases that would stop them getting ill in the first place, and added that this needed to change.

He outlined three principles that will guide the couple's investments:

• to bring scientists and engineers together
• to build tools and technology that advance research
• to grow the movement to fund more science around the world

Ms Chan added that they had already committed $600m to creating a new research centre called the Biohub, which will bring together engineers, computer scientists, biologists, chemists and other innovators.

The Biohub will initially work on two projects. The first is the Cell Atlas, a "map" that describes the different types of cells that control the body's major organs.

The second is the Infectious Disease Initiative, which will try to develop new tests and vaccines to tackle HIV, Ebola, Zika and other new diseases. Mr Zuckerberg predicted that by 2100 the average life expectancy would be beyond 100 years.

But he cautioned that it would take years before the couple's fund led to the creation of new medical treatments and further time before they could be applied to patients.

Microsoft's co-founder Bill Gates - who has funded his own health research via the Bill & Melinda Gates Foundation - appeared at the event to praise the announcement. He described it as "very bold and ambitious" but added that "we desperately need this science".

Long-term goals

Mr Zuckerberg and Ms Chan announced in December 2015 that they planned to give away 99% of their shares in Facebook to fund good causes following the birth of their daughter.

The organisation's stated mission is to make long-term investments in work that advances human potential and promotes equality.