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Thursday, 31 January 2019

First child given pioneering CAR-T cancer therapy

Eleven year old Yuvan, with parents Vinay and Sapna
Yuvan, 11, with parents, Vinay and Sapna
An 11-year-old has become the first NHS patient to receive a therapy that uses the body's own cells to fight cancer.

Yuvan Thakkar, who has a form of leukaemia, was given the personalised treatment at Great Ormond Street Hospital (GOSH), in London, after conventional cancer treatments failed.
Kymriah
Kymriah is a personalised cancer immunotherapy
CAR-T involves removing immune cells and modifying them in a laboratory so they can recognise cancer cells.
Yuvan in hospital

Previously, it was available only as part of a clinical research trial. The CAR-T therapy, called Kymriah, costs £282,000 per patient, but the NHS has negotiated a undisclosed lower price with the manufacturer, Novartis.


And the money will come from the Cancer Drugs Fund, set up to fast-track access to the most promising treatments.

Kymriah is licensed to treat patients up to 25 years old with B-cell acute lymphoblastic leukaemia (ALL), for whom other treatments have failed.